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Fibrosis in the context of respiratory diseases primarily affects the lungs. This condition is often a result of chronic inflammation or injury to lung tissue, which leads to the accumulation of excess fibrous connective tissue. Various respiratory diseases, such as interstitial lung disease, pulmonary fibrosis, or asbestosis, specifically target lung parenchyma and result in scar tissue formation.

As the lung tissue becomes fibrotic, its elasticity diminishes, leading to restricted airflow and impaired gas exchange. This development can significantly impact respiratory function and the overall oxygenation of the blood. In contrast, while other organs such as the liver and kidneys can also develop fibrosis due to different pathologies, in the context of respiratory diseases, the lungs are the most affected organ, highlighting the specificity of pulmonary fibrosis in these conditions.